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KMID : 0359920100290010153
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Korean Journal of Nephrology
2010 Volume.29 No. 1 p.153 ~ p.157
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A Case of Clopidogrel-induced Neutropenia in Chronic Renal Failure
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Hong Gi-Yeon
Seon Han-Gyung
Cheong Joon-Gu
Joo Sae-Kyung
Kang Min-Kyoung
Lee Ji-Eun
Kim Ju-Hwan
Koo Seung-Won
Park Kyoung-Mi
Lee So-Young
Kim Hyung-Jong
Yang Dong-Ho
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Abstract
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Clopidogrel, a thienopyridine derivative, is an anti-platelet agent that acts as an antagonist of the platelet adenosine diphosphate receptor and considered for essential prophylaxis for intracoronary stent thrombosis in the treatment of ischemic heart disease. Clopidogrel is considered as safe as aspirin but a few cases of severe hematologic adverse reactions associated with clopidogrel had been reported such as neutropenia, aplastic anemia, thrombocytopenic purpura, and thrombocytopenia. We report a rare case of neutropenia induced by clopidogrel in chronic renal failure in a patient who underwent percutaneous coronary intervention.
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KEYWORD
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Clopidogrel, Neutropenia, Chronic renal failure
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